Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum Proliferation

[Image: see text] In Leishmania the glutathione/glutathione reductase eukaryotic redox sys-tem is replaced by the unique trypanothione/trypanothione reductase (TR) system. In vitro, silver is a more effective TR inhibitor than antimony, the first line drug against leishmaniasis in most endemic count...

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Détails bibliographiques
Auteurs principaux: Baiocco, Paola, Ilari, Andrea, Ceci, Pierpaolo, Orsini, Stefania, Gramiccia, Marina, Di Muccio, Trentina, Colotti, Gianni
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2010
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017975/
https://ncbi.nlm.nih.gov/pubmed/24900299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1002629
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