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Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum Proliferation
[Image: see text] In Leishmania the glutathione/glutathione reductase eukaryotic redox sys-tem is replaced by the unique trypanothione/trypanothione reductase (TR) system. In vitro, silver is a more effective TR inhibitor than antimony, the first line drug against leishmaniasis in most endemic count...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical Society
2010
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017975/ https://ncbi.nlm.nih.gov/pubmed/24900299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1002629 |
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