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Targeting Trypanothione Reductase, a Key Enzyme in the Redox Trypanosomatid Metabolism, to Develop New Drugs against Leishmaniasis and Trypanosomiases

The protozoans Leishmania and Trypanosoma, belonging to the same Trypanosomatidae family, are the causative agents of Leishmaniasis, Chagas disease, and human African trypanosomiasis. Overall, these infections affect millions of people worldwide, posing a serious health issue as well as socio-econom...

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Vydáno v:Molecules
Hlavní autoři: Battista, Theo, Colotti, Gianni, Ilari, Andrea, Fiorillo, Annarita
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221613/
https://ncbi.nlm.nih.gov/pubmed/32326257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25081924
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