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Targeting CD4 Coreceptor Expression to Postselection Thymocytes Reveals That CD4/CD8 Lineage Choice Is neither Error-Prone nor Stochastic

The mechanism by which CD4/CD8 lineage choice is coordinated with TCR specificity during positive selection remains an unresolved problem in immunology. The stochastic/selection model proposes that CD4/CD8 lineage choice in TCR-signaled CD4(+)CD8(+) thymocytes occurs randomly and therefore is highly...

詳細記述

保存先:
書誌詳細
出版年:J Immunol
主要な著者: Adoro, Stanley, Erman, Batu, Sarafova, Sophia D., Van Laethem, François, Park, Jung-Hyun, Feigenbaum, Lionel, Singer, Alfred
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217309/
https://ncbi.nlm.nih.gov/pubmed/18981117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.181.10.6975
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