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The Mystery of Rap1 Suppression of Oncogenic Ras
Decades ago, Rap1, a small GTPase very similar to Ras, was observed to suppress oncogenic Ras phenotype, reverting its transformation. The proposed reason, persisting since, has been competition between Ras and Rap1 for a common target. Yet, none was found. There was also Rap1’s puzzling suppression...
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| Publicado no: | Trends Cancer |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7211489/ https://ncbi.nlm.nih.gov/pubmed/32249186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2020.02.002 |
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