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SUN-140 TMEPAI Inhibits SMAD 2/3 Mediated Muscle Wasting

Inhibition of myostatin and activin activity using ligand traps, such as soluble receptors, follistatin and propeptides, can markedly increase skeletal muscle mass in healthy mice and ameliorate wasting in models of cancer cachexia and muscular dystrophy. Though effective, clinical translation of th...

詳細記述

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書誌詳細
出版年:J Endocr Soc
主要な著者: Kharoud, Swati, Walton, Kelly Louise, Hagg, Adam, Goodchild, Georgia, Chen, Justin, Thomson, Rachel, Qian, Hongwei, Gregorevic, Paul, Harrison, Craig Anthony
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207501/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1585
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