Viral-mediated gene therapy for the muscular dystrophies: Successes, limitations and recent advances

Por Odom, Guy L., Gregorevic, Paul, Chamberlain, Jeffrey S.
Publicado em 2006

Changes in contractile activation characteristics of rat fast and slow skeletal muscle fibres during regeneration

Por Gregorevic, Paul, Plant, David R, Stupka, Nicole, Lynch, Gordon S
Publicado em 2004

Transduction of Skeletal Muscles with Common Reporter Genes Can Promote Muscle Fiber Degeneration and Inflammation

Por Winbanks, Catherine E., Beyer, Claudia, Qian, Hongwei, Gregorevic, Paul
Publicado em 2012

Systemic microdystrophin gene delivery improves skeletal muscle structure and function in old dystrophic mdx mice

Por Gregorevic, Paul, Blankinship, Michael J., Allen, James M., Chamberlain, Jeffrey S.
Publicado em 2008

Gene Therapy of mdx Mice With Large Truncated Dystrophins Generated by Recombination Using rAAV6

Por Odom, Guy L, Gregorevic, Paul, Allen, James M, Chamberlain, Jeffrey S
Publicado em 2011

Dystrophin Delivery to Muscles of mdx Mice Using Lentiviral Vectors Leads to Myogenic Progenitor Targeting and Stable Gene Expression

Por Kimura, En, Li, Sheng, Gregorevic, Paul, Fall, Brent M, Chamberlain, Jeffrey S
Publicado em 2009

Improved Contractile Function of the mdx Dystrophic Mouse Diaphragm Muscle after Insulin-Like Growth Factor-I Administration

Por Gregorevic, Paul, Plant, David R., Leeding, Kerri S., Bach, Leon A., Lynch, Gordon S.
Publicado em 2002

Microutrophin Delivery Through rAAV6 Increases Lifespan and Improves Muscle Function in Dystrophic Dystrophin/Utrophin-deficient Mice

Por Odom, Guy L, Gregorevic, Paul, Allen, James M, Finn, Eric, Chamberlain, Jeffrey S
Publicado em 2008

β(2)-Agonist administration reverses muscle wasting and improves muscle function in aged rats

Por Ryall, James G, Plant, David R, Gregorevic, Paul, Sillence, Martin N, Lynch, Gordon S
Publicado em 2004

Fluorophore-labeled myosin-specific antibodies simplify muscle-fiber phenotyping

Por Gregorevic, Paul, Meznarich, Norman A., Blankinship, Michael J., Crawford, Robert W., Chamberlain, Jeffrey S.
Publicado em 2008

Functional Deficits in nNOSμ-Deficient Skeletal Muscle: Myopathy in nNOS Knockout Mice

Por Percival, Justin M., Anderson, Kendra N. E., Gregorevic, Paul, Chamberlain, Jeffrey S., Froehner, Stanley C.
Publicado em 2008

miR-206 Represses Hypertrophy of Myogenic Cells but Not Muscle Fibers via Inhibition of HDAC4

Por Winbanks, Catherine E., Beyer, Claudia, Hagg, Adam, Qian, Hongwei, Sepulveda, Patricio V., Gregorevic, Paul
Publicado em 2013

Using AAV vectors expressing the β(2)-adrenoceptor or associated Gα proteins to modulate skeletal muscle mass and muscle fibre size

Por Hagg, Adam, Colgan, Timothy D., Thomson, Rachel E., Qian, Hongwei, Lynch, Gordon S., Gregorevic, Paul
Publicado no Sci Rep (2016)

Modulating myosin restores muscle function in a mouse model of nemaline myopathy

Por Lindqvist, Johan, Levy, Yotam, Pati‐Alam, Alisha, Hardeman, Edna C., Gregorevic, Paul, Ochala, Julien
Publicado no Ann Neurol (2016)

TGF-β Regulates miR-206 and miR-29 to Control Myogenic Differentiation through Regulation of HDAC4

Por Winbanks, Catherine E., Wang, Bo, Beyer, Claudia, Koh, Phillip, White, Lloyd, Kantharidis, Phillip, Gregorevic, Paul
Publicado em 2011

Lentiviral transduction of rat Sertoli cells as a means to modify gene expression

Por Nicholls, Peter K., Stanton, Peter G., Rainczuk, Katarzyna E., Qian, Hongwei, Gregorevic, Paul, Harrison, Craig A.
Publicado em 2012

Interleukin-15 Administration Improves Diaphragm Muscle Pathology and Function in Dystrophic mdx Mice

Por Harcourt, Leah J., Holmes, Anna Greer, Gregorevic, Paul, Schertzer, Jonathan D., Stupka, Nicole, Plant, David R., Lynch, Gordon S.
Publicado em 2005

Systemic delivery of genes to striated muscles using adeno-associated viral vectors

Por Gregorevic, Paul, Blankinship, Michael J, Allen, James M, Crawford, Robert W, Meuse, Leonard, Miller, Daniel G, Russell, David W, Chamberlain, Jeffrey S
Publicado em 2004

Erratum to “Efficient Transduction of Skeletal Muscle Using Vectors Based on Adeno-associated Virus Serotype 6”

Por Blankinship, Michael J, Gregorevic, Paul, Allen, James M, Harper, Scott Q, Harper, Hollie, Halbert, Christine L, Miller, A Dusty, Chamberlain, Jeffrey S
Publicado em 2009

Forced expression of muscle specific kinase slows postsynaptic acetylcholine receptor loss in a mouse model of MuSK myasthenia gravis

Por Ghazanfari, Nazanin, Linsao, Erna L. T. B., Trajanovska, Sofie, Morsch, Marco, Gregorevic, Paul, Liang, Simon X., Reddel, Stephen W., Phillips, William D.
Publicado no Physiol Rep (2015)