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Using AAV vectors expressing the β(2)-adrenoceptor or associated Gα proteins to modulate skeletal muscle mass and muscle fibre size
Anabolic β(2)-adrenoceptor (β(2)-AR) agonists have been proposed as therapeutics for treating muscle wasting but concerns regarding possible off-target effects have hampered their use. We investigated whether β(2)-AR-mediated signalling could be modulated in skeletal muscle via gene delivery to the...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4789796/ https://ncbi.nlm.nih.gov/pubmed/26972746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23042 |
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