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Systemic Gene Transfer to Skeletal Muscle Using Reengineered AAV Vectors

Gene therapy of musculoskeletal disorders warrants efficient gene transfer to a wide range of muscle groups. Reengineered adeno-associated viral (AAV) vectors that selectively transduce muscle tissue following systemic administration are attractive candidates for such applications. Here we provide e...

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Detalhes bibliográficos
Main Authors: Phillips, Jana L., Hegge, Julia, Wolff, Jon A., Samulski, R. Jude, Asokan, Aravind
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253371/
https://ncbi.nlm.nih.gov/pubmed/21194026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61737-982-6_9
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