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The AAV Vector Toolkit: Poised at the Clinical Crossroads

The discovery of naturally occurring adeno-associated virus (AAV) isolates in different animal species and the generation of engineered AAV strains using molecular genetics tools have yielded a versatile AAV vector toolkit. Promising results in preclinical animal models of human disease spurred the...

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Bibliographic Details
Main Authors: Asokan, Aravind, Schaffer, David V, Jude Samulski, R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321598/
https://ncbi.nlm.nih.gov/pubmed/22273577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.287
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