Adeno-Associated Virus Type 2 (AAV2) Capsid-Specific Cytotoxic T Lymphocytes Eliminate Only Vector-Transduced Cells Coexpressing the AAV2 Capsid In Vivo

A recent clinical trial has suggested that recombinant adeno-associated virus (rAAV) vector transduction in humans induces a cytotoxic T-lymphocyte (CTL) response against the AAV2 capsid. To directly address the ability of AAV capsid-specific CTLs to eliminate rAAV-transduced cells in vitro and in v...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Li, Chengwen, Hirsch, Matthew, Asokan, Aravind, Zeithaml, Brian, Ma, Hong, Kafri, Tal, Samulski, R. Jude
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Gene Delivery
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933335/
https://ncbi.nlm.nih.gov/pubmed/17475652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00529-07
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller