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Gene Therapy of mdx Mice With Large Truncated Dystrophins Generated by Recombination Using rAAV6
Recombinant adeno-associated viral (rAAV) vector-mediated gene transfer represents a promising approach for many diseases. However, the applicability of rAAV vectors has long been hindered by the small (~4.8 kb) DNA packaging capacity. This limitation can hamper the packaging and delivery of critica...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017440/ https://ncbi.nlm.nih.gov/pubmed/20859263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.205 |
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