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Recombinant adeno-associated viral (rAAV) vectors mediate efficient gene transduction in cultured neonatal and adult microglia

Microglia are a specialized population of myeloid cells that mediate CNS innate immune responses. Efforts to identify the cellular and molecular mechanisms that regulate microglia behaviors have been hampered by the lack of effective tools for manipulating gene expression. Cultured microglia are ref...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Su, Wei, Kang, John, Sopher, Bryce, Gillespie, James, Aloi, Macarena S., Odom, Guy L., Hopkins, Stephanie, Case, Amanda, Wang, David B., Chamberlain, Jeffrey S., Garden, Gwenn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547919/
https://ncbi.nlm.nih.gov/pubmed/25708596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13081
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