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Systemic delivery of genes to striated muscles using adeno-associated viral vectors
A major obstacle limiting gene therapy for diseases of the heart and skeletal muscles is an inability to deliver genes systemically to muscles of an adult organism. Systemic gene transfer to striated muscles is hampered by the vascular endothelium, which represents a barrier to distribution of vecto...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1365046/ https://ncbi.nlm.nih.gov/pubmed/15273747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1085 |
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