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Systemic delivery of adeno-associated viral vectors

For diseases like muscular dystrophy, an effective gene therapy requires bodywide correction. Systemic viral vector delivery has been attempted since early 90s. Yet a true success was not achieved until mid-2000 when adeno-associated virus (AAV) serotype-6, 8 and 9 were found to result in global mus...

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Bibliografische gegevens
Gepubliceerd in:Curr Opin Virol
Hoofdauteur: Duan, Dongsheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138077/
https://ncbi.nlm.nih.gov/pubmed/27459604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2016.07.006
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