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Mitochondria-Targeted Antiaging Gene Therapy with Adeno-associated Viral Vectors
Transgenic expression of catalase in mitochondria using a transgenic strategy extends life span and prevents aging-related pathology in mice. However, transgenic overexpression is not suitable for a clinical application. Adeno-associated virus (AAV) is the most promising gene delivery vehicle. Here...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539949/ https://ncbi.nlm.nih.gov/pubmed/23929105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-556-9_13 |
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