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Mitochondria-Targeted Antiaging Gene Therapy with Adeno-associated Viral Vectors

Transgenic expression of catalase in mitochondria using a transgenic strategy extends life span and prevents aging-related pathology in mice. However, transgenic overexpression is not suitable for a clinical application. Adeno-associated virus (AAV) is the most promising gene delivery vehicle. Here...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Methods Mol Biol
Päätekijät: Li, Dejia, Duan, Dongsheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539949/
https://ncbi.nlm.nih.gov/pubmed/23929105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-556-9_13
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