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Adeno-associated viral vectors do not efficiently target muscle satellite cells

Adeno-associated viral (AAV) vectors are becoming an important tool for gene therapy of numerous genetic and other disorders. Several recombinant AAV vectors (rAAV) have the ability to transduce striated muscles in a variety of animals following intramuscular and intravascular administration, and ha...

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Bibliographic Details
Published in:Mol Ther Methods Clin Dev
Main Authors: Arnett, Andrea LH, Konieczny, Patryk, Ramos, Julian N, Hall, John, Odom, Guy, Yablonka-Reuveni, Zipora, Chamberlain, Joel R, Chamberlain, Jeffrey S
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288464/
https://ncbi.nlm.nih.gov/pubmed/25580445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.38
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