Interleukin-15 Administration Improves Diaphragm Muscle Pathology and Function in Dystrophic mdx Mice

Interleukin (IL)-15, a cytokine expressed in skeletal muscle, has been shown to have muscle anabolic effects in vitro and to slow muscle wasting in rats with cancer cachexia. Whether IL-15 has therapeutic potential for diseases such as Duchenne muscular dystrophy (DMD) is unknown. We examined whethe...

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Hauptverfasser: Harcourt, Leah J., Holmes, Anna Greer, Gregorevic, Paul, Schertzer, Jonathan D., Stupka, Nicole, Plant, David R., Lynch, Gordon S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2005
Schlagworte:
Original Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602390/
https://ncbi.nlm.nih.gov/pubmed/15793293
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