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Dystrophin Delivery to Muscles of mdx Mice Using Lentiviral Vectors Leads to Myogenic Progenitor Targeting and Stable Gene Expression

To explore whether stable transduction of myogenic stem cells using lentiviral vectors could be of benefit for treating dystrophic muscles, we generated vectors expressing a functional microdystrophin/enhanced green fluorescence protein fusion (µDys/eGFP) gene. Lentiviral vector injection into neona...

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書誌詳細
主要な著者: Kimura, En, Li, Sheng, Gregorevic, Paul, Fall, Brent M, Chamberlain, Jeffrey S
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839215/
https://ncbi.nlm.nih.gov/pubmed/19888194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.253
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