Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

Follistatin is essential for skeletal muscle development and growth, but the intracellular signaling networks that regulate follistatin-mediated effects are not well defined. We show here that the administration of an adeno-associated viral vector expressing follistatin-288aa (rAAV6:Fst-288) markedl...

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Main Authors: Winbanks, Catherine E., Weeks, Kate L., Thomson, Rachel E., Sepulveda, Patricio V., Beyer, Claudia, Qian, Hongwei, Chen, Justin L., Allen, James M., Lancaster, Graeme I., Febbraio, Mark A., Harrison, Craig A., McMullen, Julie R., Chamberlain, Jeffrey S., Gregorevic, Paul
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2012
נושאים:
Research Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384410/
https://ncbi.nlm.nih.gov/pubmed/22711699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201109091
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