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Rapamycin suppresses postnatal muscle hypertrophy induced by myostatin-inhibition accompanied by transcriptional suppression of the Akt/mTOR pathway

Myostatin (MSTN) is a well-known negative growth factor of muscle mass, and studies have shown that MSTN-inhibition would be a potential strategy to treat muscle atrophy seen in various clinical conditions. Recent studies suggest that MSTN-inhibition induces skeletal muscle hypertrophy through up-re...

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Publicado en:Biochem Biophys Rep
Autores principales: Choi, Dong hyuck, Yang, Jinzeng, Kim, Yong Soo
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362869/
https://ncbi.nlm.nih.gov/pubmed/30805561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.12.009
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