Sirtuin 1 Inhibiting Thiocyanates (S1th)—A New Class of Isotype Selective Inhibitors of NAD(+) Dependent Lysine Deacetylases

Sirtuin 1 (Sirt1) is a NAD(+) dependent lysine deacetylase associated with the pathogenesis of various diseases including cancer. In many cancer types Sirt1 expression is increased and higher levels have been associated with metastasis and poor prognosis. However, it was also shown, that Sirt1 can h...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Oncol
Main Authors: Wössner, Nathalie, Alhalabi, Zayan, González, Jessica, Swyter, Sören, Gan, Jin, Schmidtkunz, Karin, Zhang, Lin, Vaquero, Alejandro, Ovaa, Huib, Einsle, Oliver, Sippl, Wolfgang, Jung, Manfred
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2020
נושאים:
Oncology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203344/
https://ncbi.nlm.nih.gov/pubmed/32426286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00657
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