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Identification of Bichalcones as Sirtuin Inhibitors by Virtual Screening and In Vitro Testing
Sirtuins are nicotinamide adenine dinucleotide (NAD(+))-dependent class III histone deacetylases, which have been linked to the pathogenesis of numerous diseases, including HIV, metabolic disorders, neurodegeneration and cancer. Docking of the virtual pan-African natural products library (p-ANAPL),...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6017733/ https://ncbi.nlm.nih.gov/pubmed/29443909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020416 |
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