Загрузка...

IL-21 is a broad negative regulator of IgE class switch recombination in mouse and human B cells

IgE antibodies may elicit potent allergic reactions, and their production is tightly controlled. The tendency to generate IgE has been thought to reflect the balance between type 1 and type 2 cytokines, with the latter promoting IgE. Here, we reevaluated this paradigm by a direct cellular analysis,...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Exp Med
Главные авторы: Yang, Zhiyong, Wu, Chung-An M., Targ, Sasha, Allen, Christopher D.C.
Формат: Artigo
Язык:Inglês
Опубликовано: Rockefeller University Press 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201927/
https://ncbi.nlm.nih.gov/pubmed/32130409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190472
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!