Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions

Ig heavy chain (IgH) class-switch recombination (CSR) replaces the IgH Cμ constant region exons with one of several sets of downstream IgH constant region exons (e.g., Cγ, Cε, or Cα), which affects switching from IgM to another IgH class (e.g., IgG, IgE, or IgA). Activation-induced cytidine deaminas...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Tingting, Franklin, Andrew, Boboila, Cristian, McQuay, Amy, Gallagher, Michael P., Manis, John P., Khamlichi, Ahmed Amine, Alt, Frederick W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840363/
https://ncbi.nlm.nih.gov/pubmed/20133637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915072107
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados