Trib1 regulates T cell differentiation during chronic infection by restraining the effector program

In chronic infections, the immune response fails to control virus, leading to persistent antigen stimulation and the progressive development of T cell exhaustion. T cell effector differentiation is poorly understood in the context of exhaustion, but targeting effector programs may provide new strate...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Exp Med
मुख्य लेखकों: Rome, Kelly S., Stein, Sarah J., Kurachi, Makoto, Petrovic, Jelena, Schwartz, Gregory W., Mack, Ethan A., Uljon, Sacha, Wu, Winona W., DeHart, Anne G., McClory, Susan E., Xu, Lanwei, Gimotty, Phyllis A., Blacklow, Stephen C., Faryabi, Robert B., Wherry, E. John, Jordan, Martha S., Pear, Warren S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Rockefeller University Press 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201917/
https://ncbi.nlm.nih.gov/pubmed/32150623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190888
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