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Trib1 regulates eosinophil lineage commitment and identity by restraining the neutrophil program
Eosinophils and neutrophils are critical for host defense, yet gaps in understanding how granulocytes differentiate from hematopoietic stem cells (HSCs) into mature effectors remain. The pseudokinase tribbles homolog 1 (Trib1) is an important regulator of granulocytes; knockout mice lack eosinophils...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6543518/ https://ncbi.nlm.nih.gov/pubmed/30917956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2018872218 |
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