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Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation

Eosinophil chemotaxis and survival within tissues are key components in the development of tissue eosinophilia and subsequent effector responses. In this study, we demonstrate a novel mechanism of eosinophil autoregulation affecting migration and survival mediated through Notch signaling. We show fo...

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Detalhes bibliográficos
Principais autores: Radke, Amy L., Reynolds, Lauren E., Melo, Rossana C. N., Dvorak, Ann M., Weller, Peter F., Spencer, Lisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662649/
https://ncbi.nlm.nih.gov/pubmed/19171875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-155937
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