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Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation

Eosinophil chemotaxis and survival within tissues are key components in the development of tissue eosinophilia and subsequent effector responses. In this study, we demonstrate a novel mechanism of eosinophil autoregulation affecting migration and survival mediated through Notch signaling. We show fo...

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Détails bibliographiques
Auteurs principaux: Radke, Amy L., Reynolds, Lauren E., Melo, Rossana C. N., Dvorak, Ann M., Weller, Peter F., Spencer, Lisa A.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662649/
https://ncbi.nlm.nih.gov/pubmed/19171875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-155937
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