Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans

Eosinophils release their granule proteins extracellularly through exocytosis, piecemeal degranulation, or cytolytic degranulation. Findings in diverse human eosinophilic diseases of intact extracellular eosinophil granules, either free or clustered, indicate that eosinophil cytolysis occurs in vivo...

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Main Authors: Ueki, Shigeharu, Melo, Rossana C. N., Ghiran, Ionita, Spencer, Lisa A., Dvorak, Ann M., Weller, Peter F.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2013
Teme:
Phagocytes, Granulocytes, and Myelopoiesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596967/
https://ncbi.nlm.nih.gov/pubmed/23303825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-432088
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