Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans

Eosinophils release their granule proteins extracellularly through exocytosis, piecemeal degranulation, or cytolytic degranulation. Findings in diverse human eosinophilic diseases of intact extracellular eosinophil granules, either free or clustered, indicate that eosinophil cytolysis occurs in vivo...

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Detalhes bibliográficos
Main Authors: Ueki, Shigeharu, Melo, Rossana C. N., Ghiran, Ionita, Spencer, Lisa A., Dvorak, Ann M., Weller, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596967/
https://ncbi.nlm.nih.gov/pubmed/23303825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-432088
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