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Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans

Eosinophils release their granule proteins extracellularly through exocytosis, piecemeal degranulation, or cytolytic degranulation. Findings in diverse human eosinophilic diseases of intact extracellular eosinophil granules, either free or clustered, indicate that eosinophil cytolysis occurs in vivo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ueki, Shigeharu, Melo, Rossana C. N., Ghiran, Ionita, Spencer, Lisa A., Dvorak, Ann M., Weller, Peter F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596967/
https://ncbi.nlm.nih.gov/pubmed/23303825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-432088
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