Human Eosinophils Secrete Preformed, Granule-Stored Interleukin-4 Through Distinct Vesicular Compartments

Secretion of interleukin-4 (IL-4) by leukocytes is important for varied immune responses including allergic inflammation. Within eosinophils, unlike lymphocytes, IL-4 is stored in granules (termed specific granules) and can be rapidly released by brefeldin A (BFA)-inhibitable mechanisms upon stimula...

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Hauptverfasser: Melo, Rossana C. N., Spencer, Lisa A., Perez, Sandra A. C., Ghiran, Ionita, Dvorak, Ann M., Weller, Peter F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715427/
https://ncbi.nlm.nih.gov/pubmed/16190985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2005.00344.x
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