Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation

Eosinophil chemotaxis and survival within tissues are key components in the development of tissue eosinophilia and subsequent effector responses. In this study, we demonstrate a novel mechanism of eosinophil autoregulation affecting migration and survival mediated through Notch signaling. We show fo...

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Bibliographic Details
Main Authors: Radke, Amy L., Reynolds, Lauren E., Melo, Rossana C. N., Dvorak, Ann M., Weller, Peter F., Spencer, Lisa A.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2009
Subjects:
Phagocytes, Granulocytes, and Myelopoiesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662649/
https://ncbi.nlm.nih.gov/pubmed/19171875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-155937
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