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Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation

Eosinophil chemotaxis and survival within tissues are key components in the development of tissue eosinophilia and subsequent effector responses. In this study, we demonstrate a novel mechanism of eosinophil autoregulation affecting migration and survival mediated through Notch signaling. We show fo...

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Main Authors: Radke, Amy L., Reynolds, Lauren E., Melo, Rossana C. N., Dvorak, Ann M., Weller, Peter F., Spencer, Lisa A.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662649/
https://ncbi.nlm.nih.gov/pubmed/19171875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-155937
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