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Fixed Dosing of Liposomal Amphotericin B in Morbidly Obese Individuals
In this prospective study, we examined the pharmacokinetics of 1 and 2 mg/kg liposomal amphotericin B in 16 morbidly obese individuals (104–177 kg). Body size had no effect on clearance. We recommend a fixed dose in patients ≥100 kg (ie, 300 or 500 mg rather than the current dose of 3 and 5 mg/kg, r...
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| Gepubliceerd in: | Clin Infect Dis |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7201409/ https://ncbi.nlm.nih.gov/pubmed/31588493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz885 |
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