Implications for IV posaconazole dosing in the era of obesity

BACKGROUND: The prevalence of obesity has shown a dramatic increase over recent decades. Obesity is associated with underdosing of antimicrobial drugs for prophylaxis and treatment. Posaconazole is a broad-spectrum triazole antifungal drug licensed for prophylaxis and treatment of invasive fungal in...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Wasmann, Roeland E, Smit, Cornelis, van Donselaar, Marieke H, van Dongen, Eric P A, Wiezer, René M J, Verweij, Paul E, Burger, David M, Knibbe, Catherijne A J, Brüggemann, Roger J M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069473/
https://ncbi.nlm.nih.gov/pubmed/31971567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz546
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