Population pharmacokinetics of vancomycin in obesity: Finding the optimal dose for (morbidly) obese individuals

AIMS: For vancomycin treatment in obese patients, there is no consensus on the optimal dose that will lead to the pharmacodynamic target (area under the curve 400–700 mg h L(−1)). This prospective study quantifies vancomycin pharmacokinetics in morbidly obese and nonobese individuals, in order to gu...

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Pubblicato in:Br J Clin Pharmacol
Autori principali: Smit, Cornelis, Wasmann, Roeland E., Goulooze, Sebastiaan C., Wiezer, Marinus J., van Dongen, Eric P.A., Mouton, Johan W., Brüggemann, Roger J.M., Knibbe, Catherijne A.J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015748/
https://ncbi.nlm.nih.gov/pubmed/31661553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14144
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