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Dosing Recommendations for Vancomycin in Children and Adolescents with Varying Levels of Obesity and Renal Dysfunction: a Population Pharmacokinetic Study in 1892 Children Aged 1–18 Years

Vancomycin is an effective but potentially nephrotoxic antibiotic commonly used for severe infections. Dosing guidelines for vancomycin in obese children and adolescents with or without renal impairment are currently lacking. This study describes the pharmacokinetics of vancomycin in a large pediatr...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:AAPS J
Main Authors: Smit, Cornelis, Goulooze, Sebastiaan C., Brüggemann, Roger J. M., Sherwin, Catherine M., Knibbe, Catherijne A. J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer International Publishing 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038958/
https://ncbi.nlm.nih.gov/pubmed/33839974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-021-00577-x
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