A Prospective Clinical Study Characterizing the Influence of Morbid Obesity on the Pharmacokinetics of Gentamicin: Towards Individualized Dosing in Obese Patients

BACKGROUND AND OBJECTIVE: Gentamicin is an aminoglycoside antibiotic predominantly used in bloodstream infections. Although the prevalence of obesity is increasing dramatically, there is no consensus on how to adjust the dose in obese individuals. In this prospective clinical study, we study the pha...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Smit, Cornelis, Wasmann, Roeland E., Goulooze, Sebastiaan C., Hazebroek, Eric J., Van Dongen, Eric P. A., Burgers, Desiree M. T., Mouton, Johan W., Brüggemann, Roger J. M., Knibbe, Catherijne A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768900/
https://ncbi.nlm.nih.gov/pubmed/31016671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00762-4
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