The mammalian cytosolic thioredoxin reductase pathway acts via a membrane protein to reduce ER-localised proteins

Folding of proteins entering the mammalian secretory pathway requires the insertion of the correct disulfides. Disulfide formation involves both an oxidative pathway for their insertion and a reductive pathway to remove incorrectly formed disulfides. Reduction of these disulfides is crucial for corr...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Cao, Xiaofei, Lilla, Sergio, Cao, Zhenbo, Pringle, Marie Anne, Oka, Ojore B. V., Robinson, Philip J., Szmaja, Tomasz, van Lith, Marcel, Zanivan, Sara, Bulleid, Neil J.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197872/
https://ncbi.nlm.nih.gov/pubmed/32184267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.241976
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires