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Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER

Folding of proteins entering the secretory pathway in mammalian cells frequently requires the insertion of disulfide bonds. Disulfide insertion can result in covalent linkages found in the native structure as well as those that are not, so‐called non‐native disulfides. The pathways for disulfide for...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Poet, Greg J, Oka, Ojore BV, van Lith, Marcel, Cao, Zhenbo, Robinson, Philip J, Pringle, Marie Anne, Arnér, Elias SJ, Bulleid, Neil J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331760/
https://ncbi.nlm.nih.gov/pubmed/28093500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695336
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