ERdj5 Is the ER Reductase that Catalyzes the Removal of Non-Native Disulfides and Correct Folding of the LDL Receptor

ERdj5 is a member of the protein disulfide isomerase family of proteins localized to the endoplasmic reticulum (ER) of mammalian cells. To date, only a limited number of substrates for ERdj5 are known. Here we identify a number of endogenous substrates that form mixed disulfides with ERdj5, greatly...

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Main Authors: Oka, Ojore Benedict Valentine, Pringle, Marie Anne, Schopp, Isabel Myriam, Braakman, Ineke, Bulleid, Neil John
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906653/
https://ncbi.nlm.nih.gov/pubmed/23769672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.05.014
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