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Thiol-disulfide exchange between the PDI family of oxidoreductases negates the requirement for an oxidase or reductase for each enzyme

The formation of disulfides in proteins entering the secretory pathway is catalysed by the protein disulfide isomerase (PDI) family of enzymes. These enzymes catalyse the introduction, reduction and isomerization of disulfides. To function continuously they require an oxidase to reform the disulfide...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Oka, Ojore B.V., Yeoh, Hui Y., Bulleid, Neil J.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613490/
https://ncbi.nlm.nih.gov/pubmed/25989104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141423
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