The Reduction Potential of the Active Site Disulfides of Human Protein Disulfide Isomerase Limits Oxidation of the Enzyme by Ero1α

Disulfide formation in newly synthesized proteins entering the mammalian endoplasmic reticulum is catalyzed by protein disulfide isomerase (PDI), which is itself thought to be directly oxidized by Ero1α. The activity of Ero1α is tightly regulated by the formation of noncatalytic disulfides, which ne...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Chambers, Joseph E., Tavender, Timothy J., Oka, Ojore B. V., Warwood, Stacey, Knight, David, Bulleid, Neil J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2010
Ábhair:
Protein Synthesis and Degradation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937950/
https://ncbi.nlm.nih.gov/pubmed/20657012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.156596
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla