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Is protein disulfide isomerase a redox-dependent molecular chaperone?

Protein disulfide isomerase (PDI) is a multifunctional protein catalysing the formation of disulfide bonds, acting as a molecular chaperone and being a component of the enzymes prolyl 4-hydroxylase (P4H) and microsomal triglyceride transfer protein. The role of PDI as a molecular chaperone or polype...

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Detalles Bibliográficos
Main Authors: Lumb, Richard A., Bulleid, Neil J.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC139105/
https://ncbi.nlm.nih.gov/pubmed/12485997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf685
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