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Molecular Bases of Cyclic and Specific Disulfide Interchange between Human ERO1α Protein and Protein-disulfide Isomerase (PDI)

In the endoplasmic reticulum (ER) of human cells, ERO1α and protein-disulfide isomerase (PDI) constitute one of the major electron flow pathways that catalyze oxidative folding of secretory proteins. Specific and limited PDI oxidation by ERO1α is essential to avoid ER hyperoxidation. To investigate...

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Detalhes bibliográficos
Main Authors: Masui, Shoji, Vavassori, Stefano, Fagioli, Claudio, Sitia, Roberto, Inaba, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091233/
https://ncbi.nlm.nih.gov/pubmed/21398518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.231357
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