Different Interaction Modes for Protein-disulfide Isomerase (PDI) as an Efficient Regulator and a Specific Substrate of Endoplasmic Reticulum Oxidoreductin-1α (Ero1α)

Protein-disulfide isomerase (PDI) and sulfhydryl oxidase endoplasmic reticulum oxidoreductin-1α (Ero1α) constitute the pivotal pathway for oxidative protein folding in the mammalian endoplasmic reticulum (ER). Ero1α oxidizes PDI to introduce disulfides into substrates, and PDI can feedback-regulate...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Lihui, Niu, Yingbo, Zhu, Li, Fang, Jingqi, Wang, Xi'e, Wang, Lei, Wang, Chih-chen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223321/
https://ncbi.nlm.nih.gov/pubmed/25258311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602961
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