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ERp18 regulates activation of ATF6α during unfolded protein response
Activation of the ATF6α signaling pathway is initiated by trafficking of ATF6α from the ER to the Golgi apparatus. Its subsequent proteolysis releases a transcription factor that translocates to the nucleus causing downstream gene activation. How ER retention, Golgi trafficking, and proteolysis of A...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6670016/ https://ncbi.nlm.nih.gov/pubmed/31368601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100990 |
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