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Phosphotyrosine-based Phosphoproteomics for Target Identification and Drug Response Prediction in AML Cell Lines

Acute myeloid leukemia (AML) is a clonal disorder arising from hematopoietic myeloid progenitors. Aberrantly activated tyrosine kinases (TK) are involved in leukemogenesis and are associated with poor treatment outcome. Kinase inhibitor (KI) treatment has shown promise in improving patient outcome i...

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Dades bibliogràfiques
Publicat a:Mol Cell Proteomics
Autors principals: van Alphen, Carolien, Cloos, Jacqueline, Beekhof, Robin, Cucchi, David G. J., Piersma, Sander R., Knol, Jaco C., Henneman, Alex A., Pham, Thang V., van Meerloo, Johan, Ossenkoppele, Gert J., Verheul, Henk M. W., Janssen, Jeroen J. W. M., Jimenez, Connie R.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196578/
https://ncbi.nlm.nih.gov/pubmed/32102969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001504
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