Phosphotyrosine-based Phosphoproteomics for Target Identification and Drug Response Prediction in AML Cell Lines

Acute myeloid leukemia (AML) is a clonal disorder arising from hematopoietic myeloid progenitors. Aberrantly activated tyrosine kinases (TK) are involved in leukemogenesis and are associated with poor treatment outcome. Kinase inhibitor (KI) treatment has shown promise in improving patient outcome i...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: van Alphen, Carolien, Cloos, Jacqueline, Beekhof, Robin, Cucchi, David G. J., Piersma, Sander R., Knol, Jaco C., Henneman, Alex A., Pham, Thang V., van Meerloo, Johan, Ossenkoppele, Gert J., Verheul, Henk M. W., Janssen, Jeroen J. W. M., Jimenez, Connie R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196578/
https://ncbi.nlm.nih.gov/pubmed/32102969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001504
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